Clinical Trials Now Enrolling

Click on the following trials for more information:

Cotton-O’Neil Clinical Research Center
823 SW Mulvane Street

COPD

• A 26-week treatment, multicenter, randomized, double-blind, double-dummy, placebo-controlled, adaptive, seamless, parallel-group study to assess the efficacy, safety and tolerability of two doses of investigational drug in patients with COPD (Chronic Obstructive Pulmonary Disease).

Asthma

• A 26-week treatment, multicenter, randomized, double-blind, double-dummy, parallel-group study to assess the safety of two doses of investigational drug in patients with moderate to severe persistent asthma using salmeterol as an active control.

Parkinson's Disease

• A prospective, multi-center, randomized, open-label study with blinded raters to evaluate the effects of immediate versus delayed switch to Stalevo on motor function and quality of life in patients with Parkinson's disease with end-of-dose wearing off.

Proteinuria

• A research study to compare the effects of statins on urinary protein excretion in hypercholesterolaeamic non-diabetic patients with moderate proteinuria.

Hyperlipidemia

• A study to evaluate the efficacy and safety of an investigational drug versus atorvastatin in patients with mixed hyperlipidemia.

Post Herpetic Neuralgia

• A 16-week treatment, multicenter, randomized, double-blind, placebo-controlled, parallel group, study of the analgesic effects of RN624 in adult patients with post-herpetic neuralgia (PHN)

Chronic Low Back Pain

• Phase II Randomized, Double-Blind, Placebo And Active Controlled, Multi-Center, Parallel Group Proof Of Concept Study Of The Analgesic Effects Of RN624 In Adult Patients With Chronic Low Back Pain.

Cotton-O’Neil Clinical Research Center
Behavioral Health at Stormont-Vail West
3700 SW 7th Avenue

Schizophrenia

• A 16-week, multi-center, open-label study evaluating the safety, tolerability, and efficacy of switching from quetiapine to an investigational drug in subjects diagnosed with schizophrenia or schizoaffective disorder.

Bipolar I Depression

• A six week double blind multi center placebo controlled study evaluating the efficacy and safety of flexible doses of oral ziprasidone as add on adjunctive therapy with lithium, valproate or lamotrigine in Bipolar I Depression.

Major Depressive Disorder

• A Phase 11a Multicenter, Randomized, Double-Blind, Double Dummy, and Placebo-and Active-Controlled Study to Investigate the Safety and Efficacy of an Investigational Medication Administered to Individuals with Major Depressive Disorder

Cotton-O’Neil Clinical Research Center
Diabetes & Endocrinology
3520 SW 6th Street

Type 2 Diabetes

• Comparison of two therapeutic strategies for treating type 2 diabetic patients poorly controlled with insulin associated with oral antidiabetic drugs:  6 month proof of concept study.

Type 2 Diabetes

• A Phase 3, Open-Label, Three-Group Parallel Study to Evaluate the Efficacy and Safety of Human Insulin Inhalation Powder (HIIP) in Patients with Type 2 Diabetes Treated with Once-Daily Insulin Glargine

Type 2 Diabetes

• A Phase 3, open label, crossover study to evaluate the efficacy and safety of human insulin inhalation powder (HIIP) compared with once-daily insulin glargine in insulin-naïve patients with type 2 diabetes on oral meds. (56 weeks, 16 visits, 12 phone visits, 8 PFT’s)

Type 2 Diabetes

• A research study to compare the effects of statins on urinary protein excretion in hypercholesterolaeamic diabetic patients with moderate proteinuria.

Type 2 Diabetes with CV Risk

• A randomized double-blind, placebo–controlled-parallel-group study to determine whether, in patients with type 2 diabetes at high risk for cardiovascular and renal events, aliskiren, on top of conventional treatment, reduces cardiovascular and renal morbidity and mortality.

Cotton-O’Neil Clinical Research Center
Digestive Health Center
720 SW Lane Street

Irritable Bowel Syndrome with Diarrhea

• A randommized, double-blind, placebo controlled study of an investigational drug in treatment of Irritable Bowel Syndrome with Diarrhea.

Ulcerative Colitis

• A Randomized, Double-Blind, Placebo-Controlled evaluation of the safety, efficacy, and Pharmacokinetics of multiple doses of Basiliximab, with concomitant Corticosteroids, in Steroid-Refractory Ulcerative Colitis.

Crohn's Disease

• A Phase 3b, multi-center, double-blind, placebo-controlled, randomized trial to examine the corticosteroid-sparing effect of certolizumab pegol in patients with moderate to severe crohn’s disease.

Crohn's Disease

• A phase 3, multicenter, placebo-controlled, randomized, double blind study to evaluate the safety and efficacy of PROCHYMAL (ex vivo cultured adult human mesenchymal stem cells) intravenous infusion for the induction of remission in subjects experiencing treatment-refractory moderate-to-severe crohn’s disease.

Crohn's Disease

• A 5-Year Registry study of Humira (adalimumab) in Subjects with moderately to severely active Crohn’s Disease